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BioProcess International
bioprocessintl.com > upstream-processing > multi-cycle-high-throughput-growth-media-optimization-using-batch-bayesian-optimization

Multicycle highthroughput growth batch Bayesian optimization

3+ hour, 30+ min ago   (167+ words) This study evaluates Batch Bayesian Optimization as a robust alternative using Sporosarcina pasteurii to optimize microbial growth media. Click below to begin your download. In silico simulations revealed that BBO outperformed DoE by an average of 14%. This success translated effectively…...

BioProcess International
bioprocessintl.com > cell-line-development > optimizing-cell-line-development-for-antibody-derivatives-build-in-quality-from-the-start

Optimizing Cell-Line Developing for Antibody Derivatives

3+ mon, 3+ week ago   (504+ words) Traditional cell-line development approaches would seem to require adjustments to accommodate the distinctive needs of new and complex antibody formats. But as BPI's managing editor learns from an expert in mammalian expression systems, the key for antibody derivatives might just…...

BioProcess International
bioprocessintl.com > qa-qc > ebook-quality-and-analytics-technologies-evolve-to-provide-insight-into-new-processes-and-products

Quality and Analytics: Insight into Processes and Products

5+ mon, 4+ day ago   (84+ words) The authors in this eBook explore aspects of the quality and analytics in the contexts of laboratory digitization, raw-materials monitoring, and modern analytical methods. Register or log in and hit Download to get the full eBook. See BPI at BIO…...

BioProcess International
bioprocessintl.com > qa-qc > doing-more-with-less-multifidelity-optimization-in-the-biopharmaceutical-industry

Multifidelity Optimization for Biomanufacturing

5+ mon, 1+ week ago   (125+ words) Related:Validating Your NGS Assays? Here’s Our Take Figure 1 shows that the surrogate model becomes progressively closer to a true Forrester function after each iteration. In our example, we started with three initial samples and observed that the optimization can…...