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Small Language Models for Developing Agentic AI in Healthcare: A Comprehensive Systematic Review and Critical Analysis
20+ hour, 17+ min ago (169+ words) Agentic artificial intelligence (AI) systems are emerging as a transformative approach in healthcare, enabling autonomous task execution through integrated reasoning and tool use. While early implementations have largely relied on large language models (LLMs), growing evidence suggests that smaller language…...
Safety Audit of a Large Language Model for Lay Self-Triage Using Japanese Symptom Vignettes: Persistent Red-Flag Under-Triage Despite Improved Reproducibility Under Near-Deterministic Decoding
1+ week, 2+ day ago (402+ words) Introduction: Large language models are increasingly discussed as tools for patient-facing symptom assessment, but safe self-triage depends on the concrete next action recommended to the user rather than on generic urgency language alone. We audited whether a commercially deployed general-purpose…...
Decomposing Persona Prompts for Simulated Clinical Reasoning: A Two-by-Two Factorial In Silico Experiment of Time Pressure and Safety Prioritization
1+ week, 3+ day ago (309+ words) Background: Persona prompting is widely used to steer large language models (LLMs), but its effects on safety-critical clinical reasoning are not well characterized. Methods: We performed a two-by-two factorial in silico experiment crossing time-pressure framing (high versus low) with optimization…...
Size-Dependent Performance of Abnormal-Focused U-Net Segmentation for Mammographic Lesion Detection: A Two-Stage Hybrid Training Approach
2+ week, 4+ day ago (438+ words) Introduction Breast cancer screening mammography faces challenges from variable radiologist performance and missed cancers. Deep learning segmentation models offer promise for automated lesion detection, but most training datasets are biased toward normal cases, limiting performance on clinically relevant abnormalities. Methods…...
Artificial Intelligence and Machine Learning in Diagnostic Pathology: A Systematic Review of Applications, Challenges, and Clinical Implications
3+ week, 1+ day ago (212+ words) Artificial intelligence (AI) and machine learning (ML) are transforming diagnostic medicine, particularly in pathology, where image-based interpretation is central to clinical decision-making. This systematic review aimed to examine recent advances, performance outcomes, and practical challenges associated with incorporating AI and ML…...
The Role of Generative Artificial Intelligence in the Diagnosis and Treatment of Malocclusion
3+ week, 2+ day ago (281+ words) Background Malocclusion is a prevalent dental disorder characterized by the improper alignment of the teeth and jaws, which adversely affects oral function and aesthetics. Traditional diagnosis and treatment planning procedures are time-consuming and rely heavily on expert evaluation. Recent developments…...
Assessing the Reliability of the ORADIII (Oral Radiology Artificial Intelligence Diagnostic - Version 3) Software Application in Rendering a Diagnosis: A Retrospective Study
3+ week, 4+ day ago (324+ words) Introduction Accurate interpretation of radiographic images is crucial for general dentists in making diagnoses and treatment decisions for their patients, yet the reliability of their diagnoses is often uncertain. This study evaluates the diagnostic efficacy of the differential diagnosis software…...
Publishing in the Era of Artificial Intelligence: What Do Medical Research Journals Expect?
3+ week, 5+ day ago (123+ words) Artificial intelligence (AI) is now embedded across medical research and practice, reshaping how evidence is generated and evaluated. Rather than lowering standards, AI has intensified editorial expectations within medical journals. Editors prioritise clinically meaningful knowledge over technical novelty, demanding a…...
Digital Medicine and Artificial Intelligence in Chronic Myeloid Leukemia: Current Applications, Challenges, and Future Directions
1+ mon, 1+ week ago (1180+ words) Chingiz Asadov " Aytan Shirinova " Zohra Alimirzoyeva " Aypara Hasanova Cite this article as: Asadov C, Shirinova A, Alimirzoyeva Z, et al. (February 20, 2026) Digital Medicine and Artificial Intelligence in Chronic Myeloid Leukemia: Current Applications, Challenges, and Future Directions. Cureus 18(2): e103951. doi:10.7759/cureus.103951 In…...
Comparison of Deep Learning Architectures for Cardiac Contour Segmentation in Catheterization Radiographs
1+ mon, 3+ week ago (399+ words) Introduction Accurate cardiac image segmentation is essential for quantitative assessment of cardiac anatomy and function. Manual segmentation, while considered the reference standard, is time-consuming and subject to inter- and intra-observer variability. Deep learning (DL) models, particularly convolutional neural networks (CNNs), have…...