4+ hour, 24+ min ago  (1753+ words) Arnold, F. H. Design by directed evolution. Acc. Chem. Res. 31, 125131 (1998). Packer, M. S. & Liu, D. R. Methods for the directed evolution of proteins. Nat. Rev. Genet. 16, 379394 (2015). Arnold, F. H. Directed evolution: bringing new chemistry to life. Angew. Chem. Int. Ed. Engl. 57, 41434148 (2018). Wang, Y. et al. Directed evolution: methodologies and…...

1+ hour, 4+ min ago  (524+ words) This study aims to elucidate the causal mechanism through which big data applications affect firms" price markups. Accordingly, a theoretical analytical framework is constructed, as illustrated in Fig.1. This paper extends the theoretical model proposed by Antoniades32 and constructs a heterogeneous…...

9+ hour, 51+ min ago  (1696+ words) This section introduces relevant research on multi-class segmentation of skin cancer whole-slide images (WSI) based on deep learning, covering three main areas: skin cancer image segmentation using multi-attention encoders, medical image segmentation via large model fine-tuning, and the application of…...

1+ day, 1+ hour ago  (1295+ words) Nature Protocols (2026)Cite this article Single-use components eliminate the need for a dedicated clean room facility while automation simplifies the production and purification process, lowering the cost and time required to produce therapeutic monoclonal antibodies. Data for this Protocol can…...

1+ day, 6+ hour ago  (1649+ words) a Original oracle bone inscription rubbing images showing typical degradation, including cracks, noise, and variable stroke intensity. b Segmented character samples extracted from these rubbings: "(he), "(tian), "(lu), "(fu), "(tu), "(yang), "(zai), and "(bing), illustrating the diversity of glyph shapes…...

1+ day, 9+ hour ago  (1727+ words) Overall, these results establish that the predictive eyelid response reflects the uncertainty inherent in the full stimulus probability distribution. These results show that CSpkprior does not appear to be present at the first instance that the cerebellar cortex encounters high-uncertainty…...

1+ day, 3+ hour ago  (259+ words) University of Florence, Florence, Italy. In their recent Comment article, Eddy Keming Chen et al. argue that current large language models (LLMs) already display human-level intelligence, based on behavioural evidence (see Nature 650, 3640; 2026). I suggest that this framing obscures a fundamental…...

3+ mon, 2+ day ago  (1598+ words) Various attacks on Federated Learning. Local model accuracy (performance): Accuracy is treated as one evaluation factor rather than the sole criterion, preventing adversaries from exploiting artificially inflated local performance. Gradient deviation from global model (anomaly detection): The deviation between client…...

5+ day, 3+ hour ago  (1250+ words) School of Chemistry, The University of Glasgow, University Avenue, Glasgow, UK L.C. conceived the idea and research plan together with S.P. and M.J. S.P. built and developed the workflow for the implementation of ACRA module, with contribution of M.J. S.P. and M.J. implemented the experimental setup. M.J. and…...

5+ day, 23+ hour ago  (1626+ words) npj Wireless Technology has APC waivers available that can be allocated upon acceptance on an ad-hoc basis. For additional information, contact the Journal Publisher, Timothy Tella. We provide a detailed comparative analysis of these models over wireless channels, with a…...