47+ min ago   (250+ words) Now, researchers from Hokkaido University have developed a new, fast, and accurate way to predict these metal-binding sites. Their method, called PRIME (Probe-based Identification of Metal-binding sites), is described in Nature Communications and uses a deep-learning approach to solve this…...

6+ day, 23+ hour ago   (399+ words) Scientists have combined Artificial Intelligence (AI), genetics and gut microbiome analysis to shed new light on one of the most serious complications of Crohn’s disease: intestinal fibrosis, the irreversible scarring of the bowel that often leads to surgery. Publishing their…...

1+ week, 2+ day ago   (220+ words) Figure 1: Conceptual overview of spatial and single-cell data integration, illustrating how cell type labels and transcriptomic information are transferred from a reference onto a spatial tissue map. Credit: AI-generated image created using Google Gemini (2026). For those seeking broader context on…...

1+ week, 6+ day ago   (250+ words) Researchers at Duke University School of Medicine have developed an artificial intelligence framework that can redesign proteins on a scale previously seen only in natural evolution. The tool can create shorter, longer, and highly modified versions of proteins while preserving…...

2+ week, 20+ hour ago   (321+ words) “Right now, everybody gets the same dose,” says Joyita Dutta, professor in the Riccio College of Engineering at UMass Amherst. “That essentially leaves the therapy’s potential untapped, to the extent that it’s suboptimal for a given patient. Measuring how much…...

2+ week, 2+ day ago   (1536+ words) The majority of lead compounds fail before they become valid candidates for preclinical testing. Of the candidates that do make it to the preclinical stage, most will never reach clinical trials. And of those that enter human studies, only one…...

2+ week, 5+ day ago   (639+ words) Researchers at Yale School of Medicine have conducted the first comprehensive structural analyses of a class of proteins whose dysfunction is associated with neurodegenerative diseases. In two new studies published in Cell and Molecular Cell, researchers investigated, at the atomic…...

4+ week, 16+ min ago   (287+ words) Technology Networks Deep learning approaches have transformed how scientists predict activity and function of DNA sequences in the genome A new AI tool called Corgi (Context-aware Regulatory Genomics Inference), developed by Martin Vingron's bioinformatics group at the Max Planck Institute…...

4+ week, 2+ day ago   (594+ words) “Pathologists have been looking at disorganized structure for years,” says Kevin Gardner, MD, PhD, chair of the department of pathology and cell biology at Columbia University Irving Medical Center and senior author of the study. “What topology allows us to…...

1+ mon, 44+ min ago   (167+ words) Technology Networks When cells respond to an infection, inflammation or a tumour, the activity of thousands of genes changes, altering their gene expression profiles. Analysing this activity helps researchers understand how cells change state and adapt their function. However, conventional…...