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Expanded Seq-Scope method boosts gene-mapping resolution within tissues
12+ hour, 7+ min ago (391+ words) In 2021, a technology developed at University of Michigan, called Seq-Scope, revolutionized the ability to map gene activity within intact tissue at microscopic resolution, enabling researchers to measure all expressed mRNA molecules and determine precisely where they are located within the…...
How particle shape and size analysis supports stem cell research
2+ day, 1+ hour ago (501+ words) Stem cells are particularly interesting for researchers as they are initially undifferentiated and differentiate into specialized cells over time. In recent years, significant research has been carried out on stem cells to explore how they can aid in therapeutics. Using…...
Managing PCR cycle variability in single cell experiments
2+ day, 22+ hour ago (686+ words) Conventional PCR systems require users to set a predetermined number of cycles based on assay- and sample-specific factors. When performing single-cell sequencing experiments, this requires knowledge of the number of cells captured and the RNA content within them. Different RNA…...
Metabolite-driven AI model accurately estimates time of death
3+ day, 12+ hour ago (204+ words) Metabolite-driven AI model accurately estimates time of death'News-Medical Metabolite-driven AI model accurately estimates time of death Artificial intelligence can be used to provide a more precise time of death, which can be crucial in e.g. murder investigations. The method was developed…...
Using Artificial Intelligence to Predict Chronic Disease Through Diet and Multi-Omics Data
3+ day, 21+ hour ago (1101+ words) Using Artificial Intelligence to Predict Chronic Disease Through Diet and Multi-Omics Data'News-Medical Using Artificial Intelligence to Predict Chronic Disease Through Diet and Multi-Omics Data This article explains how artificial intelligence integrates nutritional data, machine learning, and multi-omics to improve the…...
Brain organoids show goal-directed learning in control task
1+ week, 1+ day ago (878+ words) Imagine balancing a ruler vertically in the palm of your hand: you have to constantly pay attention to the angle of the ruler and make many small adjustments to make sure it doesn't fall over. It takes practice to get…...
MULTI-evolve accelerates protein engineering with machine learning
1+ week, 1+ day ago (567+ words) Published today in Science, this work represents Arc Institute's first lab-in-the-loop framework for biological design, where computational prediction and experimental design are tightly integrated from the outset, reflecting our broader investment in AI-guided research. Our insight was to focus on…...
DeepRare AI helps shorten the rare disease diagnostic journey with evidence-linked predictions
1+ week, 1+ day ago (182+ words) A new AI-driven diagnostic framework combines clinical, genetic, and phenotypic data to help shorten the rare disease diagnostic journey while providing transparent, evidence-based reasoning for clinicians. Study: An agentic system for rare disease diagnosis with traceable reasoning. Image Credit: Mdisk…...
Why unmanaged AI reflects deeper gaps in lab workflows
1+ week, 4+ day ago (1035+ words) Artificial intelligence has moved well beyond early excitement and is now used throughout modern laboratories. Scientists routinely rely on generative models to synthesize complex results, draft protocols, and think through possible next steps in an experimental series." What's increasingly striking…...
CNN-based system improves lung nodule detection and classification
1+ week, 4+ day ago (561+ words) CNN-based system improves lung nodule detection and classification'News-Medical Be the first to rate this article CNN-based system improves lung nodule detection and classification Lung cancer remains the leading cause of cancer-related mortality worldwide. Early detection of pulmonary nodules is crucial…...